Goalkeeper Trevor Carson says the Shrimps can take confidence from going toe-to-toe with in form Wigan Athletic on Tuesday night.
Morecambe took an early lead on seven minutes through Cole Stockton, who netted his 19th League goal of the season after pouncing on a loose ball in the box.
Seconds before the break and the visitors found an equaliser courtesy of top scorer Will Keane who slotted home from close range after receiving the ball six-yards out.
Substitute Stephen Humphrys headed home the winner for the Latics on 73 minutes, ensuring their unbeaten run since 26 October continues.
"I think we went toe-to-toe for most of the game," Carson said.
"It's frustrating taking the lead and coming out the wrong end of the result, we're at the stage of the season now where performances aren't enough, but plenty of positives to take.
"I think they'll finish first or second in my honest opinion, we more than matched them at times, you can't go back so you have to take the positives into Saturday and hopefully we can turn these performances into results.
"You can't feel sorry for yourself, we have to pick ourselves up and go again."
Since joining the Club, the Northern Irishman has played all three games for the Shrimps, including our FA Cup Third Round clash at Tottenham Hotspur and last weekend's Sky Bet League One fixture against AFC Wimbledon, and Carson says he's settling in well.
He added: "It's been sort of seamless for me, the lads have welcomed me greatly.
"It's been a mixed bag of results, personally I haven't had a good run of games for a long time, I'm finding my feet as well, I feel I'll get better and better every game.
"Hopefully that'll help the boys, it's an easy group to settle into, they're all down to earth lads and hard working, honest boys.