Derek Adams says the Shrimps have no complaints after falling to defeat against Ipswich Town.
Freddie Ladapo opened the scoring early on after converting from a corner before doubling his side's advantage on 16 minutes; Conor Chaplin added a third and fourth before the break.
A quadruple change at half-time saw Dynel Simeu, Michael Mellon and Dan Crowley make their Shrimps debuts, as Morecambe held The Tractor Boys to a second half stalemate.
Speaking after the game, Derek Adams admitted his team couldn't argue with the outcome.
"We've got no complaints," he said.
"[Portman Road is] a really tough venue to come to at the best of times, we obviously knew on Saturday with Oxford beating Ipswich that it was going to be a hard night for us.
"It didn't start too well for us because they got a massive break, we cleared the ball off the top of our defender's head, it's hit our player in the face and it's fallen for their player to get the first goal.
"Quite quickly after that, we made a mistake in the middle of the park, we gave the ball away, they break on us and I think it's actually slightly offside, the second goal, then they get a third and then a fourth right on half-time.
"Second half, we worked ever so hard to keep the scoreline down."
Following his quadruple half-time substitution, Adams praised his new arrivals for how they played on their debuts.
"It was never going to be easy, we made four substitutions at half-time, the reason for that was to give players game time," he added.
"We were out of the game, the game was finished, we were never going to draw it, we were never going to win it.
"To be fair, the players who came on acquitted themselves well.
"It was important to give these players some game time, I think coming away to Ipswich Town, one of the biggest clubs in this league, we just worked away and tried to stay in the game as long as we could."